Chapter 1: Conceptualization First some history: Kraepelin is the underlying grade in this chapter. Differentiated manic-depressive disease from derangement praecox (SCZ). unify melancholia (DEP) and circular psychoses (BPAD, SAFD) into one category. His fundamental insight was that counter is samara. Bleueler woolly the distinction again, putting SCZ and BPAD on a spectrum. SCZ sx were key and affective sx were non-specific. He set the stage for the unipolar-bipolar distinction. unipolar vs. bipolar: G/J spend much time tilt that unipolar-bipolar belief is less helpful than the idea of recurrence. Heterogeneity: Unipolar illness very heterogeneous group. So is bipolar. Early salmagundi schemes (1) turn out different epidemiology between MD, Md, dM and dm groups. Rates: umteen studies show that unipolar:bipolar ~1:1. So what is the unipolar/bipolar distinction: Phenomenology of Depression| bipolar| Unipolar| inhering Course| | | Age of ons et| Young| senescent| | press range| Wider range| # sequences| more(prenominal)| little| Length scuttle| piteouser| Longer| Cycle length| Longer| shorter| Precipitant of installation| more than important at onset| ?| Inter-episode mood lability| more(prenominal)| less(prenominal)| | | | Marital Status| Not a RF| RF| | | | Epedimiology| | | Life time risk| 1.
5%| 10-15%| Gender| M=F| F>M| SA| to a greater extent| less(prenominal)| | | | transmissible science| More hereditary| little| | | | Biological| | | upset aesthesia| Less| More| Sleep duration| Long| piddling | Seasonal| D-fall/winter M-spring/summer|! D-spring| | | | Pharm| | | Response to AD| Less| More| Speed of response to AD| More| Less| Tolerance to ADs| More freq| Less freq| Switch w/ ADs| More| Less| Prophylactic response to ADs| Less| More| about notes on mania: 1) unipolar mania is probably empyrean (<10% of BPAD). 2) Primacy of mania (2): all depression follows excitation issuing (mania, hypomania,...If you want to get a full essay, order it on our website:
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